Conducting a Drug Search

In this workflow, we will demonstrate the process of conducting a drug search and showcase the various outcomes attainable through the drug result page. To initiate the search, we will access the "Drug Finder" on the main home page of Synapse and search for the widely used drug, Ibuprofen.

Upon entering the drug name, the drug will appear in the drop-down list:

After clicking on the name and pressing "Search", you will be directed to the following page where you will have all the information available:

On the left-hand side, there are multiple filters available to refine the search results. While we currently have only one result in this case, these filters are particularly useful when dealing with a larger number of results. In the center of the page, you will find the primary information regarding the drug, encompassing its structure, synonyms, target mechanism, active indications, and more. By utilizing the slider at the bottom of the page, you can scroll across the screen to view additional data points pertaining to the drug.

Anything that you find is hyperlinked, when you hover over it, you will see actual links that you can click on to take you directly to the homepage of an organization or a drug type. Everything you see is quite interactive, so you can click on it to learn more.

Furthermore, it is worth noting that our current search is exclusively focused on Ibuprofen as a drug. However, in the top left-hand corner next to "Ibuprofen," you can access a drop-down menu to explore other data points.

You have the option to select one or multiple data points from the drop-down menu. For instance, if you wish to learn more about clinical trials or news associated with the drug, you can click on those options. In this workflow, we will choose "All" and click on the search icon on the right side. This action will display all available information concerning the drug. At the top of the page, you will find an overview of the data, including statistics such as 59 News Articles, 768 Clinical Trials, and so on.

You will also be able to look into the drug of interest in more depth by clicking on the hyperlink name shown below:

This is where we can access the overview of Ibuprofen. Synonyms and various related variations are also visible. You can expand the view by clicking on "+78" to reveal additional information. Numerous synonyms associated with Ibuprofen are accessible from this page.

As mentioned earlier, any text with a blue underline is clickable. If you are interested in the organization associated with the drug, the platform's intuitive nature allows you to navigate directly to the overview of that company or organization, along with related information.

Another valuable aspect, particularly for drug discovery purposes in understanding ibuprofen, is the R&D (Research and Development) status. You can either scroll down or click on the corresponding tab on the top of the page. The R&D status provides information regarding clinical trials and approvals for indications such as fever, pain, arthritis, ankle injuries, and others. You can examine the phases of the clinical trials and determine their approval status, as the interface offers interactive features.

To analyze clinical trials related to a specific indication, you can access the Clinical Trial by scrolling down or clicking on the tab located at the top of the page.

Here, a heat map is presented, which proves highly beneficial in monitoring trials accurately. For example, it indicates an increase in phase one trials for Pain.

Finally, it is important to note that in this workflow, you have the option to set email alerts for your drug of interest using the "Set alert" feature.

By utilizing this feature, you will receive updates regarding any Clinical Trial and R&D Status changes related to the drug you searched for. More detailed information regarding this feature can be found here.

Drug Finder Structure Search

You can use Structure Search to search for corresponding drugs using chemical structures directly in Synapse. This enables R&D users to identify new opportunities for therapeutic development and monitor new innovations related to their chemical compounds.​