In this comprehensive workflow, we will explore the fascinating world of drug analysis using two powerful platforms: the Chemical platform and the Synapse platform. Our main objective is to identify potential drugs, understand their structures, and then use the Synapse platform to gather more detailed and comprehensive information about these drugs. By following this workflow, you will understand how both platforms are interconnected, aiding in drug analysis.
To begin, let's navigate to the home page of the Chemical platform and use the search bar to look for a drug of interest. For this example, we will search for Diazepam. Once you select Diazepam from the drop-down menu, the drug's structure will automatically appear in the prominent white box at the center of the page:
Click the blue "Search Structures" button to proceed to the next page, where you will find all the structures associated with Diazepam. Locate and click on the first structure, which corresponds to Diazepam, and you will be directed to the detailed page displaying comprehensive information about the structure.
On the structure detail page, you will discover a wealth of information concerning the drug's structure. This includes Taxonomy information, clinical trial data, source details, and other pertinent data.
You may have observed that certain drug-related information, such as R&D status, involved organizations, approval details, etc., is not extensively available on the Chemical platform. However, this valuable data can easily be accessed on the Synapse platform. To seamlessly transition from the Chemical platform to Synapse, click on the "View drug information in Synapse" button, conveniently located near the top right corner of the structure detail page:
Clicking on this button will take you to the Drug detail page, where you will have access to an abundance of comprehensive data about Diazepam.
From here, you can utilize other functions of Synapse as well, including comparing Diazepam with other drugs. To do this, simply click on the "Start Compare" button.
If you are interested in receiving email alerts about any changes related to the drug, you can make use of the "Set Alert" function.
In conclusion, this workflow presented a dynamic and synergistic approach to drug analysis, harnessing the potential of both the Chemical and Synapse platforms. By initiating our search for potential drugs on the Chemical platform and understanding their structures, we gained valuable insights into potential drug candidates. However, we recognized the limitations of the Chemical platform in providing comprehensive drug-related information, leading us to seamlessly transition to the Synapse platform. There, we unlocked a vast repository of in-depth data, including R&D status, approval information, clinical trial data, and more, empowering us with a holistic perspective on our chosen drug, such as Diazepam.
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