Bio Premium - Combined Search

This article will cover the basics of how to use Combined Search in Bio Premium. 

The combined search allows the user to search a maximum of six queries at a time with a combination of inputs. The results will display patents that contain any combination of the searched query.  

1. Navigate to the combined search option and begin inputting your queries. 

Tip: You can customize the names and preferences of each query you input. You can also use different input types for each query (E.g. Amino acid sequence for Query 1 and Nucleotide input for Query 2). 

2. Click search to navigate to the results page. On the top half of the result page, you will have data analytics of the result and the bottom half will generate a heat map of the patents containing relevant results. It should be noted that the Analysis charts are dynamic to help you quickly get to the key data of interest.

Tip: Hovering over the graphs will provide a breakdown of sequence and patent data for each query.  

The heat map displays the number of matching sequences in each patent and the alignment identities for each sequence found. Using the legend on the right you can determine which patents have sequences with the highest alignment identity. 

Tip: For patents with multiple sequences matched within a patent, hover your cursor over the number tile to get a breakdown of sequence data for all matched sequences.   

3. To further review the patents click “View in Analytics”.  

However, instead of or before going into Analytics, you are able to further refine your results using the filters on the left-hand side of the page, ultimately improving workflow efficiency. These filters are similar to those found in Analytics

In addition to the filters, there is also an option to narrow down your results to show patents that have the sequence in the claims section. You can do this by clicking on the 'In claims' checkbox and this filter will then retain patents only if the given sequence is mentioned in the resulting patent claims.

Finally, you also have the option to apply Patent family groupings to the resulting data set allowing you to display the most relevant family representative. this can be done by clicking on the small gear icon which will open up the following pop-up screen:

4. Once the results are taken to the Analytics platform they will be organized into families. At this point, all the functionalities of Analytics can be used to refine, save, and analyze patents.  

5. After refining your results, they can be saved in a Bio enabled workspace. 

Tip: The workspaces are now enabled to show sequence data from the bio platform when you click the Seq Code. Clicking view results from this pop-out box will redirect you to the Bio platform. To further analyze the patent click on the patent name or title.   

Literature Combined Search

You can also use Combined search when searching for sequences in non-patent literature involving multiple queries. Particularly, you are able to utilize Combined Search in literature sources to
help identify prior art. In addition, you can also use filters on the left-hand side of the page such as keyword, literature source, journal, author, etc., to further narrow down results and improve workflow efficiency. To search for literature, make sure to select the check box next to 'literature' on the Combined Search home page, and then select the 'Literature' tab at the top of the page.

The display of the results is similar to the display when viewing patents, with the Analysis charts on the top of the page and the heat map below that.